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If these (cell) walls could talk: Georgia stem cell research in danger

If passed, the state law would halt stem cell research

CAREY O'NEIL

Issue date: 3/19/09 Section: News
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Media Credit: LESLEY ONSTOTT
[Click to enlarge]
Media Credit: LESLEY ONSTOTT
[Click to enlarge]
(Top) Alex Squires, 20, a student from Richmond Hill, Ga., is majoring in cognitive science and cellular biology and works in the animal science laboratory. (Left) Kate Hodges, from Athens, creates glass tools to move stem cells from dish to dish. Research on stem cells could be stopped if the new state law is passed.
Media Credit: LESLEY ONSTOTT
(Top) Alex Squires, 20, a student from Richmond Hill, Ga., is majoring in cognitive science and cellular biology and works in the animal science laboratory. (Left) Kate Hodges, from Athens, creates glass tools to move stem cells from dish to dish. Research on stem cells could be stopped if the new state law is passed.
[Click to enlarge]
On the heels of President Barack Obama's termination of an eight-year ban on stem cell research, the Georgia Senate is debating a bill that would essentially continue old restrictions.

Dr. Steve Stice, director of the Regenerative Bioscience Center, said he worries that if the bill passes, it could have serious repercussions for the University.

"We've got great students at UGA, and we'd like to recruit even more," he said in a phone interview Wednesday. "It's hard to recruit students and faculty to come to a University in a state that's viewed as being basically backward in their view of technology."

Despite possible setbacks from the state, Stice said he was excited about the Obama administration's changes because the majority of his lab's funding comes from the federal government.

"It's not opening the floodgates on research dollars, which really would be fantastic, but it's the first step hopefully toward more funding," he said.

One of the RBC's largest federal grants comes from the Department of Defense, which is asking researchers to develop a medicine that can be injected in broken bones, stimulating growth and cutting healing time by more than 91 percent - from six months to two weeks, Stice said.

"The idea is that today when people have major injuries to their limbs, there's a lot of defects and loss of bone and it results oftentimes in amputation, and when limbs are not amputated, the patient can be in bed for months at a time," Stice explained.

According to Stice, most of the RBC is researching cells related to neurodegenerative diseases such as Alzheimer's and Parkinson's.

Tulsi Patel, a senior from Acworth and researcher at the RBC, studies these cells but worries about her ability to continue her research if the state law is passed.

"It will undo any progress that Obama does in Georgia," she said in a phone interview Tuesday. "I don't think we'd make a lot of progress for a long time if we don't get as much funding."

Either way, Patel said cures for serious diseases could be a long way off.

"A lot of stem cell work going on right now is ground work," she said. "We don't take a disease and work on it, we just work on the development."

If passed, the state law would stop the derivation of any new embryonic stem cell lines, where researchers take a three to five-day-old embryo and grow its cells in a laboratory.

"Basically it's a hollow sphere with a bunch of cells in it," Patel explained. "You take a few of those cells and grow them in vitro. They basically keep dividing, indefinitely as far as we know."

The lines the RBC are working on were derived before the Bush Administration's ban on new lines. According to Patel, the cells the RBC used to create its line were "taken from defective embryos, so these were embryos that couldn't turn into babies."

Stice said he believes the RBC's ability to receive funding becomes unjustly caught up in issues surrounding abortion. He explained that fertility clinics attempting in vitro fertilization often are unsuccessful, resulting in embryos with no chance at life.

"Those are discarded every day, and that would be something that I would think, no matter what side you're on, would be a morally acceptable way of developing stem cells," he said.

Patel expressed her excitement that in the coming years, this whole debate could be irrelevant.

"Just in the last year or two, labs found that if you take skin cells and activate five genes you basically turn them back into what seems to be an embryonic type cell," she said. "It has the potential to take the [pro-life] problem out [of stem cell research]."

Regardless, the debate is still happening in the Georgia senate, and Stice said he worries about the RBC's future.

"If the bill passed, would it stop our research tomorrow? No, but it would have a major impact over time on our institution."
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Viewing Comments 1 - 10 of 17

Gary Pitts

posted 3/19/09 @ 9:21 AM EST

When is the bias going to ever stop? I'm afraid the liberal indoctrination of the education system in this country is so deep now, that it may never come back to using common sense. (Continued…)

(5 replies)   Details   Reply to this comment

My uncle ain't a monkey

posted 3/19/09 @ 10:01 AM EST

Every time you say "stem cell" it makes baby Jesus cry.

PN

posted 3/19/09 @ 10:02 AM EST

Gary, you want to know why the government forces people to pay for something they disagree with? It's a little something called "representative democracy. (Continued…)

ugaprof

posted 3/19/09 @ 10:14 AM EST

No one objects to stem cell research. The controversy is about destruction of human embryos to get stem cells. Fortunately, when I was an embryo, this wasn't done to me. (Continued…)

jam

posted 3/19/09 @ 10:34 AM EST

hi

CaliforniaLottoResult

posted 3/19/09 @ 10:40 AM EST

very interesting...

Winfield J. Abbe

posted 3/19/09 @ 10:45 AM EST

While I am a frequent critic of Georgia government, the State has every right to question and regulate this type of research. Furthermore, since these cells are studied in vitro, this means they are under an artificial energy supply outside the normal human environment. (Continued…)

(2 replies)   Details   Reply to this comment

Mary Bagwell

posted 3/19/09 @ 11:16 AM EST

Once again a Georgia governor makes me embarrassed to be from this state. Haven't you heard that this research is on embryos that would be discarded anyway? Why is it better to throw the away than to use them for research? They will never become babies and since there is a possibility that they could be used for research that might benefit those who are suffering from various diseases it would seem that this would be be the much better way. (Continued…)

GO SQUIRES!

posted 3/19/09 @ 12:36 PM EST

Stem cells are harvested from embryos that will never be used, just discarded if not used, why not use them to save or better the lives of others instead?
If you use the killing of the innocent as an excuse, these are never going to be born, just frozen until past their "use by" date. (Continued…)

Matthew Sheahan

posted 3/19/09 @ 1:38 PM EST

No disrespect intended, but people opposed to stem cell research reside in the same intellectual plane as those who think taking their photograph will steal their soul. (Continued…)

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